This single 5FU treatment, mimicking the single dose in vitro, was sufficient to drive increased TOM20 expression (Fig
However, the GSH levels of mucosa remained unchanged, indicating a direct disturbing effect of either agent on mucosal integrity, independent of GSH (Table 1)
Research involving Glutathione commonly investigates its interaction with: Cellular oxidative-stress pathways Reactive oxygen species (ROS)-related mechanisms Antioxidant-support pathways involving compounds such as Vitamin C and Vitamin E Cellular detoxification and antioxidant-support signaling Cellular-resilience and physiological-maintenance pathways Because of its broad antioxidant research profile, Glutathione is frequently investigated in oxidative-stress, metabolic-support, healthy-aging, and physiological-resilience research models
Valente EM, Abou-Sleiman PM, Caputo V, Muqit MMK, Harvey K, Gispert S, et al
doi: 10.3389/fnins.2015.00372 100 MurphyM
And I want to, I really want to be an open book